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Table 2 Treatment characteristics and outcome of the patients included in this series

From: Upfront surgery is not advantageous compared to more conservative treatments such as observation or medical treatment for patients with desmoid tumors

Variable

Patients (n = 99, %)

Initial treatment

Local treatment (n = 60, 60.6%)

Observation/medical treatment (n = 39, 39.4%)

Biopsy

 Core needle biopsy

70, 70.7%

38, 63.3%

32, 82.1%

 Open biopsy

29, 29.3%

22, 36.7%

7, 17.9%

Total number of surgeries

 Median

1

1

0

 IQR

0–1

1–2

0–0

NSAIDs

 No

82, 82.8%

60, 100.0%

22, 56.4%

 Yes

17, 17.2%

0

17, 43.6%

Tyrosine kinase inhibitor

 No

98, 99.0%

60, 100.0%

38, 97.4%

 Yes

1, 1.0%

0

1, 2.6%

Anti-hormonal therapy + NSAIDs

 No

87, 87.9%

59, 98.3%

28, 71.8%

 Yes

12, 12.1%

1, 1.7%

11, 28.2%

Low-dose chemotherapy

 No

72, 72.7%

56, 93.3%

16, 41.0%

 Yes

27, 27.3%

4, 6.7%

23, 59.0%

Follow up period (months)

 Median

57

58.5

55

 IQR

33–86

35–96

27–85

Event

 No

71, 71.7%

41, 68.3%

30, 76.9%

 Yes

28, 28.3%

19, 31.7%

9, 23.1%

Interval between the diagnosis and event

 Median

18

19

13

 IQR

9–32

9–36

9–24

MSTS score

 Median

26

29

21

 IQR

21–30

23–30

19–29.5

  1. IQR interquartile range, NSAIDs non-steroidal anti-inflammatory drugs, MSTS Musculoskeletal Tumor Society