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Table 1 Details of the patients included in this study at baseline

From: Upfront surgery is not advantageous compared to more conservative treatments such as observation or medical treatment for patients with desmoid tumors

Variables Patients (n = 99, %) Initial treatment P value
Local treatment (n = 60, 60.6%) Observation/medical treatment (n = 39, 39.4%)
Age at diagnosis (years)
 Median 38.2 39.4 36.1 0.670
 IQR 25.4–47.7 25.5–50.8 23.8–44.3  
Sex
 Male 37, 37.4% 23, 38.3% 14, 35.9% 0.806
 Female 62, 62.6% 37, 61.7% 25, 64.1%  
Tumor site
 Abdominal wall 4, 4.0% 2, 3.3% 2, 5.1% 0.901c
 Upper extremity 10, 10.1% 9, 15.0% 1, 2.6%  
 Lower extremity 39, 39.4% 21, 35.0% 18, 46.2%  
 Girdle 31, 31.3% 20, 33.3% 11, 28.2%  
 Head and neck 6, 6.1% 2, 3.3% 4, 10.3%  
 Chest wall 9, 9.1% 6, 10.0% 3, 7.7%  
Tumor size (cm)
 Median 8 7 9 0.045a
 IQR 5–11 5–10 6–13  
Clinical presentation
 Mass 42, 42.4% 23, 38.3% 19, 48.7% 0.308d
 Pain 7, 7.1% 3, 5.0% 4, 10.3%  
 Mass + Pain 46, 46.5% 33, 55.0% 13, 33.3%  
 Functional impairment 2, 2.0% 0 2, 5.1%  
 Functional impairment + Pain 2, 2.0% 1, 1.7% 1, 2.6%  
Previous surgery or trauma at the site of the primary tumor
 Yes 14, 14.1% 9, 15.0% 5, 12.8% 0.721b
 No 85, 85.9% 51, 85.0% 34, 87.2%  
Year of diagnosis
 1999–2009 61, 61.6% 48, 80.0% 13, 33.3% < 0.001a
 2010–2018 38, 38.4% 12, 20.0% 26, 66.7%  
  1. IQR interquartile range. aThe difference was significant. bThe Fisher exact test was used. cComparison of extremity and non-extremity. dComparison of mass alone and the others