Skip to main content
Fig. 4 | BMC Musculoskeletal Disorders

Fig. 4

From: Higher aggrecan 1-F21 epitope concentration in synovial fluid early after anterior cruciate ligament injury is associated with worse knee cartilage quality assessed by gadolinium enhanced magnetic resonance imaging 20 years later

Fig. 4

Schematic figure of aggrecan showing MMP (IPEN/FFGV) and aggrecanase (TEGE/ARGS) cleavage sites in the inter-globular domain (IGD). The amino acid numberings are based on the full-length human aggrecan amino acid sequence starting with the N-terminus 1MTTL and finishing with the C-terminus STAH2415 (NCBI accession no. P16112). The positions for recognition of 3B3 and aggrecan 1-F21 antibodies are shown by dashed lines. IGD = interglobular domain; KS = keratan sulfate region; CS = chondroitin sulfate region; G = globular domains

Back to article page

BMC Musculoskeletal Disorders

ISSN: 1471-2474

Contact us