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Table 3 Vascular events, wound complications, and adverse reactions resulting from TXA

From: Comparison of the effectiveness and safety of intravenous and topical regimens of tranexamic acid in complex tibial plateau fracture: a retrospective study

Variable Control group (30 patients) i.v. group (30 patients) Topical group (30 patients) P value (between groups)
Vascular events
 DVT 3 5 3 0.661
 MI 0 0 0
 CI 0 0 0
 PE 0 0 0
 GIH 0 1 0 0.364
 Total 3 6 3 0.421
Wound complications
 Dehiscence 0 0 0
 Hematoma 0 0 0
 Edge necrosis 0 0 0
 Infection 1 0 0 0.364
 Total 1 0 0 0.364
Adverse reactions
 Epilepsy 0 0 0
 Rash 0 1 0 0.364
 Headache 2 4 1 0.338
 Nausea and Vomiting 1 1 1 1.000
 Total 3 6 2 0.260
  1. Abbreviations: TXA tranexamic acid, DVT deep vein thrombosis, MI myocardial infarction, CI cerebral infarction, PE pulmonary embolism, GIH gastrointestinal hemorrhage
  2. Chi-square test was performed for intra-group comparisons