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Table 2 Postoperative data and postoperative blood test results

From: Comparison of the effectiveness and safety of intravenous and topical regimens of tranexamic acid in complex tibial plateau fracture: a retrospective study

Variable

Control group (30 patients)

i.v. group (30 patients)

Topical group (30 patients)

P value (between groups)

Intergroup comparison

P1 P2 P3

Surgical data

 Duration of surgery (min)

117.7 ± 19.4

109.1 ± 17.5

115.3 ± 20.5

0.206a

–

–

–

 Duration of tourniquet (min)

97.3 ± 8.5

95.4 ± 10.1

101.6 ± 11.4

0.056a

–

–

–

 IBL (mL)

144.5 ± 21.1

116.5 ± 15.2

137.5 ± 19.2

<  0.001a

<  0.001

0.184

<  0.001

 TPD (mL)

156.3 ± 27.6

76.5 ± 15.2

64.1 ± 16.3

<  0.001a

<  0.001

<  0.001

0.004

Postoperative blood tests

 HB (g/dL)

  24 h

11.7 ± 1.1

12.2 ± 2.2

11.9 ± 0.8

0.430a

–

–

–

  POD#3

11.2 ± 2.4

12.5 ± 3.4

11.6 ± 1.2

0.125a

–

–

–

 Hct (%)

  24 h

33.5 ± 4.1

34.1 ± 3.9

33.7 ± 4.4

0.849a

–

–

–

  POD#3

33.7 ± 2.9

34.6 ± 2.4

34.1 ± 3.1

0.466a

–

–

–

 D-dimer (mg/L)

  24 h

9.6 ± 3.4

8.1 ± 2.9

8.4 ± 3.3

0.165a

–

–

–

  POD#3

11.2 ± 4.1

9.8 ± 3.1

10.3 ± 3.8

0.335a

–

–

–

 FIB (g/L)

  24 h

5.7 ± 2.1

5.1 ± 1.9

5.4 ± 2.3

0.546a

–

–

–

  POD#3

7.4 ± 2.6

6.4 ± 1.3

6.8 ± 2.9

0.264

–

–

–

Real Hb decrease (g/dL)

1.5 ± 0.6

0.9 ± 0.3

1.2 ± 0.4

<  0.001a

<  0.001

0.026

0.002

Transfusion rate (%)

6.7%

0

0

0.129b

–

–

–

  1. Abbreviations: POD#3 the third postoperative day
  2. P1 represents the P value obtained by comparison between control group and i.v. group;
  3. P2 represents the P value obtained by comparison between control group and topical group;
  4. P3 represents the P value obtained by comparison between i.v. group and topical group;
  5. Intergroup comparisons performed using AVONA or Chi-square test (aANOVA; bChi-square test)