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Table 2 Postoperative data and postoperative blood test results

From: Comparison of the effectiveness and safety of intravenous and topical regimens of tranexamic acid in complex tibial plateau fracture: a retrospective study

Variable Control group (30 patients) i.v. group (30 patients) Topical group (30 patients) P value (between groups) Intergroup comparison
P1 P2 P3
Surgical data
 Duration of surgery (min) 117.7 ± 19.4 109.1 ± 17.5 115.3 ± 20.5 0.206a
 Duration of tourniquet (min) 97.3 ± 8.5 95.4 ± 10.1 101.6 ± 11.4 0.056a
 IBL (mL) 144.5 ± 21.1 116.5 ± 15.2 137.5 ± 19.2 <  0.001a <  0.001 0.184 <  0.001
 TPD (mL) 156.3 ± 27.6 76.5 ± 15.2 64.1 ± 16.3 <  0.001a <  0.001 <  0.001 0.004
Postoperative blood tests
 HB (g/dL)
  24 h 11.7 ± 1.1 12.2 ± 2.2 11.9 ± 0.8 0.430a
  POD#3 11.2 ± 2.4 12.5 ± 3.4 11.6 ± 1.2 0.125a
 Hct (%)
  24 h 33.5 ± 4.1 34.1 ± 3.9 33.7 ± 4.4 0.849a
  POD#3 33.7 ± 2.9 34.6 ± 2.4 34.1 ± 3.1 0.466a
 D-dimer (mg/L)
  24 h 9.6 ± 3.4 8.1 ± 2.9 8.4 ± 3.3 0.165a
  POD#3 11.2 ± 4.1 9.8 ± 3.1 10.3 ± 3.8 0.335a
 FIB (g/L)
  24 h 5.7 ± 2.1 5.1 ± 1.9 5.4 ± 2.3 0.546a
  POD#3 7.4 ± 2.6 6.4 ± 1.3 6.8 ± 2.9 0.264
Real Hb decrease (g/dL) 1.5 ± 0.6 0.9 ± 0.3 1.2 ± 0.4 <  0.001a <  0.001 0.026 0.002
Transfusion rate (%) 6.7% 0 0 0.129b
  1. Abbreviations: POD#3 the third postoperative day
  2. P1 represents the P value obtained by comparison between control group and i.v. group;
  3. P2 represents the P value obtained by comparison between control group and topical group;
  4. P3 represents the P value obtained by comparison between i.v. group and topical group;
  5. Intergroup comparisons performed using AVONA or Chi-square test (aANOVA; bChi-square test)