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Table 3 Association between CARMEN variants and ONFH risk

From: Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population

SNP-ID Model Genotype Frequency Without adjustment With adjustment
Case Control OR (95% CI) p-value OR (95% CI) p-value
rs13177623 codominant A/A 17 42 1   1  
   A/G 133 178 0.96 (0.71–1.30) 0.794 0.95 (0.70–1.29) 0.726
   G/G 158 203 0.52 (0.29–0.95) 0.377 0.52 (0.28–0.94) 0.031
  dominant A/A 17 42 1   1  
   A/G-G/G 291 381 0.88 (0.65–1.18) 0.341 0.86 (0.64–1.16) 0.332
  recessive A/A-A/G 150 220 1   1  
   G/G 158 203 0.53 (0.30–0.95) 0.033 0.53 (0.30–0.95) 0.033
  log-additive 0.82 (0.65–1.04) 0.106 0.82 (0.65–1.03) 0.091
rs12654195 codominant G/G 25 60 1   1  
   G/T 142 174 1.05 (0.77–1.43) 0.771 1.04 (0.76–1.42) 0.831
   T/T 141 181 0.53 (0.32–0.90) 0.017 0.53 (0.32–0.90) 0.017
  dominant G/G 25 60 1   1  
   G/T-T/T 283 355 0.92 (0.68–1.23) 0.563 0.91 (0.67–1.22) 0.517
  recessive G/G-G/T 167 234 1   1  
   T/T 141 181 0.52 (0.32–0.85) 0.010 0.53 (0.32–0.86) 0.011
  log-additive 0.83 (0.66–1.03) 0.094 0.82 (0.66–1.03) 0.087
  1. 95%CI 95% Confidence interval; OR Odds ratio; SNP Single-nucleotide polymorphism
  2. p-value: Calculated by Pearson χ2 test
  3. Bold type indicates statistical significance (p < 0.05)