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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Novel transplant of combined platelet-rich fibrin Releasate and bone marrow stem cells prevent bone loss in Ovariectomized osteoporotic mice

Fig. 2

a Schematic representation of the trabecular bone area using for micro-computed tomography (micro-CT) analysis. The proximal tibia was selected for analysis within a conforming volume of interest commencing at the growth plate and extending a further longitudinal distance of 0.5 to 1.5 mm in the proximal direction to assess site-specific responses to ovariectomized and treatments. b Comparison of coronal and axial view of micro-CT images of non-ovariectomized (Non-OVX) and ovariectomized (OVX) mice. c Micro-CT analysis of bone marrow density (BMD), bone volume versus total tissue volume (BV/TV, %), trabecular number (Tb.N), and trabecular separation (Tb.Sp) in non-OVX and OVX mice eight weeks after surgery. The bars show the mean ± SD (n = 6) of each group. **P < .01; ***P < .001; ****P < .0001

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