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Table 5 Periprosthetic joint infection (PJI), individual casesa

From: Anti-rheumatic treatment and prosthetic joint infection: an observational study in 494 elective hip and knee arthroplasties

Diagnosis Type of surgery Anti-rheumatic treatment Infectious agents Treatment of PJI Outcome
RAb, seronegative TKAc Methotrexate, prednisolone S. aureus Debridement and exchange of tibial insert Healed (26 months later re-infected with the same bacteria)
RAb, seropositive TKAc Etanercept,
methotrexate
coagulase negative staphylococcus (CNS) Two-stage revision Healed
RAb, seropositive TKAc Prednisolone, azathioprine S. aureus Debridement and exchange of tibial insert Failure (chronic infection treated with suppressive antibiotics)
RAb, seropositive TKAc Methotrexate, prednisolone B. fragilis Antibiotics Failure, amputation
RAb, seropositive TKAc Methotrexate, sulfasalazine, hydroxychloroquine, prednisolone S. mitis, S. hominis Debridement and exchange of tibial insert Healed
RAb, seropositive TKAc Prednisolone coagulase negative staphylococcus (CNS) Debridement and exchange of tibial insert Healed
PsAc TKAc None coagulase negative staphylococcus (CNS) Debridement and exchange of tibial insert Healed
  1. aIn order to not compromise patient confidentiality age and sex is excluded from the table. There were 4 males and 3 females and the mean age was 64 years (range 44–70)
  2. bRheumatoid arthritis
  3. cpsoriatic arthritis