Table 5 Periprosthetic joint infection (PJI), individual cases^a

RA^b, seronegative

TKA^c

Methotrexate, prednisolone

S. aureus

Debridement and exchange of tibial insert

Healed (26 months later re-infected with the same bacteria)

RA^b, seropositive

TKA^c

Etanercept,

methotrexate

coagulase negative staphylococcus (CNS)

Two-stage revision

Healed

RA^b, seropositive

TKA^c

Prednisolone, azathioprine

S. aureus

Debridement and exchange of tibial insert

Failure (chronic infection treated with suppressive antibiotics)

RA^b, seropositive

TKA^c

Methotrexate, prednisolone

B. fragilis

Antibiotics

Failure, amputation

RA^b, seropositive

TKA^c

Methotrexate, sulfasalazine, hydroxychloroquine, prednisolone

S. mitis, S. hominis

Debridement and exchange of tibial insert

Healed

RA^b, seropositive

TKA^c

Prednisolone

coagulase negative staphylococcus (CNS)

Debridement and exchange of tibial insert

Healed

PsA^c

TKA^c

None

coagulase negative staphylococcus (CNS)

Debridement and exchange of tibial insert

Healed