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Table 3 Postoperative complications and clinical outcomes according to whether osteoporosis medication was BP or TP

From: Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: a multi-center retrospective study

 

BP

TP

p-value

Cases, n

104

55

–

Mechanical complications

76 (73.1%)

32 (58.2%)

0.045

 Subsequent vertebral fracture

47 (45.2%)

18 (32.7%)

0.18

 Screw complications

42 (40.4%)

19 (34.5%)

0.29

 Screw loosening

29 (27.9%)

18 (32.7%)

0.59

 Screw backout

13 (12.5%)

1 (1.8%)

0.024

 Rod fracture

0

0

–

 Pseudoarthrosis

9 (8.7%)

1 (1.8%)

0.091

Revision due to mechanical complications

10 (9.6%)

9 (16.4%)

0.30

Postoperative JOA

9.7 ± 3.4

9.3 ± 3.3

0.45

Recovery rate of JOA

49.0 ± 27.5

52.1 ± 25.2

0.49

Final VAS (back pain)

29.8 ± 22.5

31.3 ± 24.5

0.71

Change in VAS (back pain)

40.4 ± 30.0

41.6 ± 32.3

0.83

Final VAS (leg pain or numbness)

18.4 ± 20.4

21.2 ± 25.3

0.46

Change in VAS (leg pain or numbness)

33.5 ± 27.1

35.8 ± 30.1

0.63

  1. BP bisphosphonate, TP teriparatide, JOA Japanese Orthopaedic Association, VAS visual analogue scale