Thermogenic diagnosis of periprosthetic joint infection by microcalorimetry of synovial fluid

Table 3 Concordance of 107 detected microorganisms by synovial fluid culture and microcalorimetry

Diagnostic test		Periprosthetic joint infection (n = 46)		Aseptic failure (n = 61)
Culture	Microcalorimetry
+	+	14	S. aureus (1) E. coli (2) Streptococcus spp. (8)^a E. faecalis (1) CNS (2)	0
–	–	24		60
Total concordant		38		60
+	–	4	E. faecalis (2) CNS (1) E. coli (1)	0
–	+	4	Pseudomonas aeruginosa (1)^b CNS (1)^b	1
Total discordant		8		1

CNS coagulase-negative staphylococci, *primers not included in the PCR test kit
^a S. agalactiae (n = 4), S. mitis/oralis (n = 3), S. gordonii (n = 1)
^b In one patient, two organisms were isolated during revision surgery

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