Table 3 Characteristics of the studies examinating the effects of IL-6 174G/C genes on osteoporosis risk
First author/Year | Ethnicity | Menopause | IL-6 174G/C genotype distribution | HWE | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Chi-square test | P | |||||||
GG | GC | CC | GG | GC | CC | |||||
Ji Y F, 2019 | East Asia | PSM | 399 | 285 | 74 | 440 | 270 | 56 | 2.613 | 0.106 |
Deveci D, 2012 | Caucasian | PSM | 127 | 50 | 24 | 93 | 31 | 31 | 42.528 | 0 |
Czerny B, 2010 | Caucasian | PSM | 67 | 126 | 33 | 76 | 103 | 45 | 0.872 | 0.3503 |
Breuil V, 2009 | Caucasian | PSM | 34 | 47 | 11 | 30 | 30 | 9 | 0.12 | 0.7293 |
Magaña JJ, 2008 | Caucasian | Pre | 56 | 14 | 0 | 42 | 25 | 3 | 0.09 | 0.7645 |
Dincel E, 2008 | Caucasian | Ne | 0 | 10 | 10 | 0 | 7 | 10 | 1.143 | 0.2851 |
Kusek J, 2008 | Caucasian | PSM | 24 | 63 | 23 | 12 | 36 | 14 | 1.637 | 0.2007 |
Nordstrom A, 2004 | Caucasian | PSM | 68 | 121 | 43 | 167 | 246 | 131 | 4.565 | 0.0326 |