From: Antibiotic prophylaxis in primary and revision shoulder replacement: a systematic review
Author | Antibiotic dosage | Administration time | Mic μg/ml (mean) | Culture-negative | Culture-positive | Outcome |
---|---|---|---|---|---|---|
Pérez-Priet o[19] | Cefalosporin 2 g; Glycopeptide 1 g | 30 and 60 min before surgery | 8 | 20 | Preoperative antibiotic prophylaxis does not eliminate suspected or confirmed cultures of PJI intraoperatively. | |
Kong Ko h[20] | Cefazolin 2 g; Gentamicin 3 mg/kg. | 30 min before surgery | 0.32 | 8 | 22 | Cefazolin is not effective or sufficient to eliminate P. acnes colonies. |
Lut z[21] | Clindamycin–Ofloxacin (n = 14 PZ) Rifampicin–Ofloxacin(n = 6PZ) Clindamycin–Rifampicin (n = 3PZ) Cloxacillin–Ofloxacin(n = 2) Rrifampicin–Pristinamycin (n = 2PZ) Ceftriaxone–pristinamycin(n = 1PZ) Cefepime–Ofloxacin (n = 1PZ) Reicoplanin–Rifampicin (n = 1PZ) Clindamycin–Fusidic Acid (n = 1PZ) Clindamycin monotherapy(n = 1PZ) Vancomycin–Ceftazidime–Ciprofloxacin(n = 1PZ) | Antibiotic prophylaxis is effective for preventing infection. | ||||
Opric a[22] | Clindamycin Erythromycin Tetracycline Linezolyd Benzypenicillin Vancomycin | < 0,064–64 > < 0,064- > 128 < 0,064–32 > < 0,25–2 > < 0,008-0,125 > < 0,25–2> | It was concluded that antimicrobial tested do not always eliminate p. acnes. | |||
Matse n[23] | Ceftriaxone 2 g; Vancomycin 1 g | 30 aminutes before surgery | 7 | 3 | In the shoulder arthroplasty, the preoperative prophylaxis is not always eradicated Propionibacterium from the operative field. | |
Parad a[24] | Cefazolin Vancomicin Clindamycin | In Propionibacterium infections during shoulder arthroplasty, there are no precise clinical guidelines. | ||||
Al-Mayah i[25] | Quinolone Beta-Lactam Long-Acting Agent (Vancomycin, Teicoplanin, Ceftriaxne Ertapenem) | 1 h before surgery | 26 (8%) 136 (43%) 33 (10%) | 105 (4%) 570 (24%) 189 (8%) | Preoperative antibiotic prophylaxis, even in a single dose, is associated with negative results in culture. |