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Table 2 Study outcome

From: Antibiotic prophylaxis in primary and revision shoulder replacement: a systematic review

Author

Antibiotic dosage

Administration time

Mic μg/ml (mean)

Culture-negative

Culture-positive

Outcome

Pérez-Priet o[19]

Cefalosporin 2 g;

Glycopeptide 1 g

30 and 60 min before surgery

 

8

20

Preoperative antibiotic prophylaxis does not eliminate suspected or confirmed cultures of PJI intraoperatively.

Kong Ko h[20]

Cefazolin 2 g;

Gentamicin 3 mg/kg.

30 min before surgery

0.32

8

22

Cefazolin is not effective or sufficient to eliminate P. acnes colonies.

Lut z[21]

Clindamycin–Ofloxacin (n = 14 PZ)

Rifampicin–Ofloxacin(n = 6PZ)

Clindamycin–Rifampicin (n = 3PZ)

Cloxacillin–Ofloxacin(n = 2)

Rrifampicin–Pristinamycin (n = 2PZ)

Ceftriaxone–pristinamycin(n = 1PZ)

Cefepime–Ofloxacin (n = 1PZ)

Reicoplanin–Rifampicin (n = 1PZ)

Clindamycin–Fusidic Acid (n = 1PZ)

Clindamycin monotherapy(n = 1PZ)

Vancomycin–Ceftazidime–Ciprofloxacin(n = 1PZ)

    

Antibiotic prophylaxis is effective for preventing infection.

Opric a[22]

Clindamycin Erythromycin Tetracycline

Linezolyd Benzypenicillin Vancomycin

 

< 0,064–64 > < 0,064- > 128 < 0,064–32 > < 0,25–2 > < 0,008-0,125 > < 0,25–2>

  

It was concluded that antimicrobial tested do not always eliminate p. acnes.

Matse n[23]

Ceftriaxone 2 g;

Vancomycin 1 g

30 aminutes before surgery

 

7

3

In the shoulder arthroplasty, the preoperative prophylaxis is not always eradicated Propionibacterium from the operative field.

Parad a[24]

Cefazolin

Vancomicin

Clindamycin

    

In Propionibacterium infections during shoulder arthroplasty, there are no precise clinical guidelines.

Al-Mayah i[25]

Quinolone

Beta-Lactam

Long-Acting Agent (Vancomycin, Teicoplanin, Ceftriaxne Ertapenem)

1 h before surgery

 

26 (8%) 136 (43%) 33 (10%)

105 (4%) 570 (24%) 189 (8%)

Preoperative antibiotic prophylaxis, even in a single dose, is associated with negative results in culture.