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Table 2 Study outcome

From: Antibiotic prophylaxis in primary and revision shoulder replacement: a systematic review

Author Antibiotic dosage Administration time Mic μg/ml (mean) Culture-negative Culture-positive Outcome
Pérez-Priet o[19] Cefalosporin 2 g;
Glycopeptide 1 g
30 and 60 min before surgery   8 20 Preoperative antibiotic prophylaxis does not eliminate suspected or confirmed cultures of PJI intraoperatively.
Kong Ko h[20] Cefazolin 2 g;
Gentamicin 3 mg/kg.
30 min before surgery 0.32 8 22 Cefazolin is not effective or sufficient to eliminate P. acnes colonies.
Lut z[21] Clindamycin–Ofloxacin (n = 14 PZ)
Rifampicin–Ofloxacin(n = 6PZ)
Clindamycin–Rifampicin (n = 3PZ)
Cloxacillin–Ofloxacin(n = 2)
Rrifampicin–Pristinamycin (n = 2PZ)
Ceftriaxone–pristinamycin(n = 1PZ)
Cefepime–Ofloxacin (n = 1PZ)
Reicoplanin–Rifampicin (n = 1PZ)
Clindamycin–Fusidic Acid (n = 1PZ)
Clindamycin monotherapy(n = 1PZ)
Vancomycin–Ceftazidime–Ciprofloxacin(n = 1PZ)
     Antibiotic prophylaxis is effective for preventing infection.
Opric a[22] Clindamycin Erythromycin Tetracycline
Linezolyd Benzypenicillin Vancomycin
  < 0,064–64 > < 0,064- > 128 < 0,064–32 > < 0,25–2 > < 0,008-0,125 > < 0,25–2>    It was concluded that antimicrobial tested do not always eliminate p. acnes.
Matse n[23] Ceftriaxone 2 g;
Vancomycin 1 g
30 aminutes before surgery   7 3 In the shoulder arthroplasty, the preoperative prophylaxis is not always eradicated Propionibacterium from the operative field.
Parad a[24] Cefazolin
Vancomicin
Clindamycin
     In Propionibacterium infections during shoulder arthroplasty, there are no precise clinical guidelines.
Al-Mayah i[25] Quinolone
Beta-Lactam
Long-Acting Agent (Vancomycin, Teicoplanin, Ceftriaxne Ertapenem)
1 h before surgery   26 (8%) 136 (43%) 33 (10%) 105 (4%) 570 (24%) 189 (8%) Preoperative antibiotic prophylaxis, even in a single dose, is associated with negative results in culture.