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Table 1 Study Characteristics

From: Pre-operative denosumab is associated with higher risk of local recurrence in giant cell tumor of bone: a systematic review and meta-analysis

Study

Year

Country

No. of cases

Follow-up (months)

Site

Surgery

Quality Score

Denosumab

Control

Agarwal(19)

2018

India

25

34

12 to 24

E/K

C/W

********

Chen(15)

2018

China

20

10

3 to 36

K

Unspecified

*****

Costantino(3)

2018

Italy

25

222

> 24

E/K

C

******

Liu(18)

2016

China

1

3

> 8

E

C

****

Medellin(20)

2018

UK

7

100

> 12

E

C/W

******

Scoccianti(9)

2018

Italy

12

9

14 to 92

E/K

C

******

Tsukamoto(13)

2019

Japan

25

317

54 to 124

E/K

C/W

******

Urakawa(17)

2018

Japan

40

158

60 to 72

E/K

C

*****

Yang(22)

2018

China

6

10

> 24

K

C/W

********

Zou(21)

2018

China

8

50

21 to 321

K

C/W

******

  1. E Extremity; K Trunk; C Intralesional Curettage; W Wide Resection