Skip to main content

Table 1 Eligibility criteria

From: Effectiveness of intramuscular gluteal glucocorticoid injection versus intra-articular glucocorticoid injection in knee osteoarthritis: design of a multicenter randomized, 24 weeks comparative parallel-group trial

Inclusion criteria:
1) contacted their GPa (consultation and/or repeat pain medication prescription) due to knee OAb (ICPCc L90 or L15) during the past 5 years;
2) aged 45 years and over;
3) symptomatic knee OA for at least 3 months prior to enrolment;
4) a minimum score of 3 on the NRSd asking about the severity of knee pain averaged over the past week (0–10; 0 = no knee pain);
5) glucocorticoid injection is indicated in this patient
Exclusion criteria:
1) use of oral glucocorticoids;
2) intra-articular injection in a knee in the previous 6 months;
3) allergy to glucocorticoids;
4) local or systemic infection, recent vaccination with live attenuated vaccine;
5) type 1 diabetes mellitus, type 2 diabetes mellitus on insulin therapy, poorly controlled type 2 diabetes mellitus;
6) presence of inflammatory rheumatic diseases (such as rheumatoid arthritis, psoriatic arthritis, spondylartropathies);
7) coagulopathy, use of anticoagulants, use of dual antiplatelet therapy;
8) a history of gastric/duodenal ulcer or a present gastric/duodenal ulcer;
9) currently receiving care of an orthopaedic surgeon for OA of the hip and/or knee;
10) incapacity to complete questionnaires in Dutch;
11) incapacity to give informed consent.
  1. aGP General Practitioner bOA Osteoarthritis cICPC International Classification of Primary Care dNumeric Rating Scale