Table 6 Alleles and genotypes distribution between patients with different rate of progression of IS
From: CHD7 gene polymorphisms in female patients with idiopathic scoliosis
Independent model | Dominant model | Recessive model | |||||||
|---|---|---|---|---|---|---|---|---|---|
Allele/genotype | NP-IS N = 80 | SP-IS N = 78 | RP-IS N = 53 | P-valuea | P-value NP-IS vs. RP-ISa | P-valuea | P-value NP-IS vs. RP-ISb | P-valuea | P-value NP-IS vs. RP-ISa |
rs1017861 | |||||||||
G | 93.1 | 86.5 | 81.1 | 0.0124 | 0.0053 | ||||
A | 6.9 | 13.5 | 18.9 | ||||||
GG | 87.5 | 75.6 | 64.2 | 0.0316 | 0.005 | 0.83 | 1 | 0.0065 | 0.0029 |
GA | 11.3 | 21.8 | 33.9 | ||||||
AA | 1.3 | 2.5 | 1.9 | ||||||
rs4738824 | |||||||||
G | 83.1 | 80.8 | 81.1 | 0.85 | 0.80 | ||||
AA | 16.9 | 19.2 | 18.9 | ||||||
GG | 68.8 | 64.1 | 64.2 | 0.96 | 0.80 | 0.97 | 1 | 0.47 | 0.72 |
GA | 28.8 | 33.3 | 33.9 | ||||||
AA | 2.5 | 2.6 | 1.9 | ||||||
rs4738813 | |||||||||
T | 62.5 | 75. | 73.6 | 0.0338 | 0.08 | ||||
C | 37.5 | 25. | 26.4 | ||||||
TT | 38.8 | 62.8 | 50.9 | 0.0028 | 0.0483 | 0.06 | 0.0273 | 0.0103 | 0.23 |
CT | 47.5 | 24.4 | 47.2 | ||||||
CC | 13.8 | 12.8 | 1.9 | ||||||