CHD7 gene polymorphisms in female patients with idiopathic scoliosis

Table 5 Characteristics of patients with different progression rate of IS

	NP-IS N = 80	SP-IS N = 78	RP-IS N = 53	P-value
Age (y)	18.5 ± 1.8 (15.0–24.1)	16.9 ± 2.4 (15–26.2)	16.3 ± 7.1 (12.4–50.1)	0.12^b
Age of menarche	12.9 ± 1.3 (10.0–15.1)	13.1 ± 1.3 (10.0–16.2)	13.1 ± 1.1 (10.5–16.1)	0.22^a
Cobb angle (°)	23.9 ± 5.4 (10–30)	38.9 ± 7.9 (30–65)	62.7 ± 15.7 (39–114)	0.0001^a
Progression rate (°/month)	0.15 ± 0.21 (0.0–1.0)	0.51 ± 0.23 (0.22–0.93)	1.82 ± 0.96 (1.0–4.0)	0.0001^a
Surgical treatment	0	12.8%	84.9%	0.0001^c

Abbreviations: IS idiopathic scoliosis, NP-IS nonprogressive idiopathic scoliosis, SP-IS slowly progressive idiopathic scoliosis and RP-IS rapidly progressive idiopathic scoliosis, values shown as mean ± standard deviation (min-max), ^a- ANOVA with Bonferroni correction, ^b –Kurskal-Wallis test, ^c –Chi-square test
significant P-values (<0.05) are in bold

ISSN: 1471-2474