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Table 3 Criteria and scores of modified Pauli’s microscopic grading system within meniscus

From: Substantive molecular and histological changes within the meniscus with tears

  Score
I Surface of inner border
A. Smooth 0
B. Slight fibrillation or slightly undulating 1
C. Moderate fibrillation or markedly undulating 2
D. Severe fibrillation or disruption 3
II Cellularity
A. Normal 0
B. Diffuse hypercellularity or hypocellularity 1
C. Vacuoloid changes or cell clusters 2
D. Vacuoloid changes and cell clusters 3
III Collagen organisation/alignment and fibre organisation
A. Collagen fibres organised and homogenous eosinophilic
staining of extracellular matrix
0
B. Fewer collagen fibres unorganised or diffuse foci of hyaline or
mucinous degeneration
1
C. Most collagen fibres unorganised or confluent foci or bands of
hyaline or mucinous degeneration.
2
D. Collagen fibres unorganised and fibrocartilaginous separation
(oedema, cyst formation).
3
  1. The range of possible total scores was 0–9, which was then converted into 4 grades: G1 0–1, G2 2–4, G3 5–7, and G4 8–9. Grade 1 represents normal tissue, Grade 2 is mild degeneration, Grade 3 is moderate degeneration, and Grade 4 is severe degeneration