Fig. 4

In situ hybridisation results showing miR-455-3p and miR-381-3p levels in the meniscus. a-f Sections were counterstained with nuclear fast red solution, representative positive cells are marked with arrows, and the scale for the bar is 50 μm (insert: 25 μm). g In situ hybridisation graph showing total histopathological score in group A (normal meniscus), group B (simple meniscal tear),and group C (meniscal tear with concomitant ACL tear), taken as the product of the specific reactivity (IR) and proportion of positive cells. The values are given as the mean and the standard error of mean. Within a given group, significant difference (p < 0.05) compared with group A is denoted with (*). Significant differences (p < 0.05) between group B and group C are marked with (#). Representative results from at least three samples in each group are shown