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Table 3 Incidence rates and incidence rate ratios of surgery for systemic lupus erythematosus cohort and comparison cohort, with stratification by age group (N = 3462)

From: Risk of joint replacement surgery in Taiwanese female adults with systemic lupus erythematosus: a population-based cohort study

Type of surgery (ICD-9-CM)

Age group (years)

systemic lupus erythematosus cohort

comparison cohort

IRR (95% CI)

aIRR (95% CI)

P value

P value

No. of patients

Person-years

IR

No. of patients

Person-years

IR

THR (81.51)

20–44

8

2391.0

334.6

4

12,548.0

31.9

10.53 (3.17–34.96)

< 0.001

7.70 (2.19–27.12)

0.001

45–64

3

1087.8

275.8

2

5563.3

35.9

7.67 (1.28–45.90)

0.026

4.69 (0.64–34.07)

0.127

65–80

1

164.6

607.5

1

933.6

107.1

5.67 (0.36–90.66)

0.220

1.98 (0.10–40.49)

0.657

TKR (81.54)

20–44

1

2417.4

41.4

0

12,604.5

0.0

NC

NC

45–64

5

1071.4

466.7

10

5532.2

180.8

2.58 (0.88–7.55)

0.083

2.66 (0.90–7.90)

0.078

65–80

0

171.1

0.0

5

905.3

552.3

NC

NC

  1. aIRR adjusted incidence rate ratio, IR incidence rate, NC not calculable, THR total hip replacement surgery, TKR total knee replacement surgery
  2. aIRRs were adjusted for obesity, fracture of the lower limb, socioeconomic status and geographic region