The efficacy and safety of tranexamic acid for reducing blood loss following simultaneous bilateral total knee arthroplasty: a multicenter retrospective study

Table 2 Comparison of Blood Loss, LOS and expenses

Variable	IV group (n = 192)	Combined group (n = 135)	Control group (n = 248)	P	P1	P2	P3
TBL (mL)	1061.1 ± 689.6	988.3 ± 559.3	1685.0 ± 571.4	0.006*	0.693	0.003*	0.003*
Transfusion rate	27 (14.1%)	15 (11.1%)	57 (23.0%)	0.005*	0.818	0.018*	0.005*
Drain volume	432.9 ± 262.6	393.2 ± 250.3	663.9 ± 199.4	< 0.001*	0.348	0.005*	< 0.001*
Maximum Hb drop	28.8 ± 14.5	28.5 ± 13.4	33.4 ± 14.0	0.015*	0.710	0.025*	0.016*
Maximum Hct drop	0.082 ± 0.056	0.074 ± 0.053	0.131 ± 0.049	0.001*	0.614	0.001*	< 0.001*
LOS	7.8 ± 6.6	7.7 ± 4.8	10.1 ± 3.8	0.781	< 0.001*	< 0.001*	< 0.001*
Expenses ∆	93,625.8 ± 16,516.4	94,255.1 ± 10,453.5	99,174.1 ± 14,032.7	0.005*	0.676	0.005*	0.006*

TBL Total blood loss, Hb Hemoglobin, Hct Hematocrit, POD postoperative day. LOS: length of stay; P represents P value of IV vs combined vs control group, P1 represents P value of IV vs combined group, P2 represents P value of IV vs control group, P3 represents P value of combined vs control group
∆ Results were presented as Chinese yuan
*Significant difference

ISSN: 1471-2474