Tibiofemoral joint structural change from 2.5 to 4.5 years following ACL reconstruction with and without combined meniscal pathology

Table 6 Association between baseline tibial cartilage defect, BML scores and annual percentage increase in cartilage volume

	Cartilage Defect				BMLs
	Univariate regression coefficient (95% CI)	P Value	Multivariate regression coefficient (95% CI) ^a	P Value	Univariate regression coefficient (95% CI)	P Value	Multivariate regression coefficient (95% CI) ^a	P Value
Medial tibia	0.039 (0.006, 0.071)	0.02*	0.026 (− 0.007, 0.060)	0.12	−0.015 (− 0.025, − 0.005)	0.005*	− 0.017 (− 0.027, − 0.007)	0.001*
Lateral tibia	0.015 (0.003, 0.026)	0.01*	0.02 (0.008, 0.032)	0.002*	−0.004 (− 0.013, 0.004)	0.31	− 0.007(− 0.015, 0.002)	0.11

^a Multivariate analysis was adjusted for age, gender, BMI, baseline bone size and presence of meniscal pathology. * Significant difference (P < 0.05)

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