Cooled radiofrequency ablation of the genicular nerves for chronic pain due to osteoarthritis of the knee: a cost-effectiveness analysis based on trial data

Table 4 Primary analysis, CRFA vs IAS 6- and 12-month time horizon: deterministic mean (probabilistic sensitivity analysis mean; 95% confidence interval)

Time horizon	Intervention	QALYs	Incremental QALY gain	Costs (US$)	Incremental cost (US$)	Cost per QALY gained (US$)^a
6 months	CRFA	0.347 (0.345; 0.265, 0.420)	0.091 (0.090; −0.024, 0.198)	$2005 ($2005; $1929, $2083)	$1711 ($1711; $1632, $1791)	$18,773 ($19,053; −$58,845, $91,604)
	IAS	0.256 (0.255; 0.174, 0.335)	0.091 (0.090; −0.024, 0.198)	$295 ($294; $275, $315)	$1711 ($1711; $1632, $1791)	$18,773 ($19,053; −$58,845, $91,604)
12-months	CRFA	0.714 (0.706; 0.543, 0.853)	0.229 (0.230; 0.011, 0.440)	$2005 ($2005; $1929, $2083)	$1711 ($1711; $1632, $1791)	$7462 ($7424; $3189, $31,405)
	IAS	0.485 (0.475; 0.323, 0.630)	0.229 (0.230; 0.011, 0.440)	$295 ($294; $275, $315)	$1711 ($1711; $1632, $1791)	$7462 ($7424; $3189, $31,405)

Abbreviations: CRFA cooled radiofrequency ablation, IAS intra-articular steroid, QALY quality-adjusted life-years
^aCost per QALY gained for the comparison of CRFA with IAS

ISSN: 1471-2474