From: Host-specific factors affect the pathogenesis of adverse reaction to metal debris
 | Difference in histological grading between left and right sides | |||||
---|---|---|---|---|---|---|
No difference | 1 p | 2p | 3p | 4p | Scale | |
Macrophage sheet thickness | 18 (62%) | 9 (31%) | 2 (7%) | – |  | 0–3 p |
Lymphocyte cuff thickness | 14 (48%) | 15 (52%) | – | – |  | 0–3 p |
Degree of necrosis* | 6 (21%) | 10 (34%) | 9 (31%) | 1 (3%) | 3 (10%) | 0–4 p |
Presence of plasma cells | 26 (90%) | 3 (10%) | Â | Â | Â | Yes/no |
Presence of diffuse lymphocytic infiltration | 19 (66%) | 10 (34%) | Â | Â | Â | Yes/no |
Presence of germinal centers | 27 (93%) | 2 (7%) | Â | Â | Â | Yes/no |
Presence of granulomas* | 24 (83%) | 5 (17%) | Â | Â | Â | Yes/no |