| Thiazide use | Loop diuretic use | ||
---|---|---|---|---|
Yes (n = 4734) | No (n = 4734) | Yes (n = 2364) | No (n = 2364) | |
Cases of vertebral fracture | 138 | 108 | 99 | 67 |
Person-years | 8975.9 | 8251.3 | 3928.8 | 3740.5 |
Incidence ratea | 15.4 | 13.1 | 25.2 | 17.9 |
Univariate model | ||||
 crude HR (95% CI) | 1.18 (0.92–1.52) | 1 (ref.) | 1.40 (1.03–1.92) | 1 (ref.) |
 p value | 0.201 |  | 0.032 |  |
Multivariate modelb | ||||
 adjusted HR (95% CI) | 1.14 (0.88–1.47) | 1 (ref.) | 1.45 (1.06–1.98) | 1 (ref.) |
 p value | 0.316 |  | 0.019 |  |