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Table 3 Comorbidities in patients with multifocal and oligofocal osteonecrosis (ON)

From: Clinical characteristics and role of whole-body bone scan in multifocal osteonecrosis

Comorbidity

Multifocal ON

(n = 18/26)

Oligofocal ON

(n = 70/228)

Any ON

(N = 88/254)

Immune system disease

8

26

34

 Ulcerative colitis

1

 

1

 Rheumatoid arthritis

 

5

5

 AOSD

 

1

1

 Systemic lupus erythematosus

3

7

10

 MCD, MGN, IgA nephropathy

2

7

9

 ANCA-associated vasculitis

1

1

2

 Dermatomyositis

 

3

3

 Sarcoidosis, Behçet’s disease, vitalism

1

2

3

ESRD with KT

3

6

9

Malignancy

2

16

18

 Lung cancer

 

1

1

 Stomach cancer

1

2

3

 Renal cancer

 

2

2

 Breast cancer

1

5

6

 Neuroblastoma

 

2

2

 Rectal cancer

 

2

2

 Gall bladder cancer

 

1

1

 Hepatocellular carcinoma

 

1

1

Hematological diseases

 

4

4

 Acute myelocytic leukemia

 

1

1

 Multiple myeloma

 

1

1

 Aplastic anemia

 

2

2

Mitral valve stenosis, with operation

 

1

1

Spinal cord tumor, meningioma, pheochromocytoma

1

2

3

Craniopharyngioma, seizure

1

1

2

Osteoporosis with bisphosphonate treatment

 

2

2

Bronchiectasis

 

1

1

Facial palsy, hearing loss, trigeminal neuralgia

1

2

3

Recurrent oral ulcer, recurrent uveitis

1

1

2

Allergic disease (urticarial, Steven-Johnson), vitalism, asthma

1

5

6

Liver cirrhosis, intraperitoneal bleeding

 

3

3

  1. ON osteonecrosis, AOSD adult onset Still’s disease, MCD minimal change disease, MGN membranous glomerulonephritis, ANCA anti-neutrophil cytoplasmic antibody, ESRD end-stage renal disease, KT kidney transplantation
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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