Population (N = 185) | Patients with OHSI (N = 12) | Patients without OHSI (N = 173) | OHSI-paired controls (N = 48) | p1 | p2 | |
---|---|---|---|---|---|---|
Female sex, N° (%) of patients | 162 (87.6) | 11 (91.7) | 151 (87.3) | 44 (99.7) | 1 | 1 |
(Mean ± SD) Age at cohort inclusion, years | 38.5 ± 12.9 | 42 ± 15.6 | 38.3 ± 12.7 | 42 ± 14.9 | 0.33 | 1 |
Medium-low socioeconomic level, N° (%) of patients | 165 (89.2) | 11 (91.7) | 154 (89) | 43 (89.6) | 1 | 1 |
(Mean ± SD) Years of formal education | 11.2 ± 3.9 | 10.2 ± 4.3 | 11.3 ± 3.9 | 10.8 ± 4.2 | 0.32 | 0.66 |
Disease duration, months | 5.3 (3. 3-7.0) | 7.5 (6. 2-9.3) | 5 (2. 9-7.4) | 5 (2. 9-7.4) | 0.02 | 0.02 |
N° (%) of patients with RF | 152 (82.8) | 11 (91.7) | 141 (81.5) | 44 (99) | 0.7 | 1 |
N° (%) of patients with ACCP | 158 (85.9) | 12 (100) | 146 (84.9) | 43 (91.5) | 0.22 | 0.6 |
N° (%) of patients with erosions | 18 (9.7) | 2 (16.7) | 16 (9.2) | 5 (10.4) | 0.33 | 0.62 |
DAS28 | 5.9 (4.8-6.9) | 7 (5.4-7.7) | 6.3 (4.9-7.5) | 6.3 (4.9-7.5) | 0.27 | 0.27 |
Physician-VAS | 36 (36–49) | 51 (31-68) | 41 (30-52) | 41 (30-51.5) | 0.23 | 0.23 |
CRP, mg/dL | 0.7 (0.3-2.5) | 3.6 (0.5-7.1) | 1.2 (0.3-2.3) | 1.2 (0.3-2.3) | 0.06 | 0.06 |
ESR, mm/H | 11 (12-39) | 42 (19-74) | 26 (15-49) | 26 (15. 3-49) | 0.14 | 0.14 |
Charlson Score | 1 (1-1) | 1 (1-1) | 1 (1-1) | 1 (1-1) | 0.18 | 0.12 |
HAQ (0–3) | 1.4 (0.9-2.1) | 1.4 (1-2.3) | 1.4 (0.9-2) | 1.4 (0.9-2) | 0.73 | 0.73 |
SF-36 (0–100) | 38 (27-55) | 33 (24-56) | 34 (26-57) | 33.8 (26.4-57.4) | 0.94 | 0.94 |
Patient-overall disease-VAS | 53 (33-76) | 71 (41–92) | 62 (34-78) | 62 (34-78) | 0.29 | 0.29 |
Pain-VAS | 50 (31-73) | 61 (46–98) | 52 (33-78) | 52 (33.3-77.8) | 0.48 | 0.48 |
N° (%) of patients with DMARDs | 101 (54.6) | 7 (58.3) | 94 (54.3) | 19 (39.6) | 1 | 1 |
N° (%) of patients with corticosteroids | 72 (38.9) | 4 (33.3) | 68 (39.3) | 15 (31.3) | 0.77 | 1 |