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Table 1 Characteristics of patients with hand OA and control subjects

From: Lower serum clusterin levels in patients with erosive hand osteoarthritis are associated with more pain

 

OA patients

(n = 135)

Erosive

(n = 81)

Non-erosive (n = 54)

Controls

(n = 53)

Age, years

66.3 ± 8.3

67.6 ± 8.6*

64.3 ± 7.3

64.6 ± 7.6

Sex, female/male

120/15

74/7

46/8

48/5

CRP, mg/l

3.2 ± 3.9

3.4 ± 4.1

2.9 ± 3.7

3.3 ± 5.1

BMI, kg/m2

27.2 ± 4.2

27.5 ± 4.5

26.8 ± 3.7

NA

Disease duration, years

4.4 ± 5.2

4.4 ± 5.1

4.5 ± 5.5

NA

AUSCAN

22.5 ± 10.5

23.9 ± 11.1*

20.3 ± 9.1

NA

AUSCAN - pain

8.4 ± 4.2

9.0 ± 4.4*

7.5 ± 3.8

NA

AUSCAN - stiffness

1.9 ± 0.9

2.0 ± 0.9

1.9 ± 0.9

NA

AUSCAN - function

12.0 ± 6.4

12.8 ± 6.8

10.9 ± 5.6

NA

Algofunctional index

18.6 ± 5.9

19.5 ± 6.4

17.2 ± 4.8

NA

VAS - pain, mm

44.2 ± 22.7

46.7 ± 24.0

40.3 ± 20.3

NA

US osteophytes, n

12.8 ± 5.1

14.0 ± 4.6**

11.0 ± 5.4

NA

GS synovitis (total)

7.5 ± 8.7

9.3 ± 9.2***

4.8 ± 7.2

NA

GS synovitis (joint count)

5.5 ± 6.4

6.5 ± 6.6***

3.9 ± 5.8

NA

PD synovitis (total)

2.0 ± 2.7

2.5 ± 3.1*

1.3 ± 1.9

NA

PD synovitis (joint count)

1.7 ± 2.1

2.1 ± 2.3**

1.1 ± 1.6

NA

Knee OA, n (%)

59 (44)

35 (43)

24 (44)

NA

Hip OA, n (%)

40 (30)

27 (33)

13 (24)

NA

Knee and hip OA, n (%)

28 (21)

18 (22)

10 (19)

NA

  1. The data are presented as the mean ± the standard deviation. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with non-erosive. (AUSCAN Australian/Canadian, BMI body mass index, CRP C-reactive protein, GS gray scale, OA osteoarthritis, PD power Doppler, US ultrasound, VAS visual analogue scale)