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Table 1 Staging system for Osteonecrosis of the Knee (OK) in Sickle Cell Disease [17]

From: Use of autologous bone marrow stem cell implantation for osteonecrosis of the knee in sickle cell disease: a preliminary report

Stage

Radiological findings

1

Normal appearance, accompanied by pain

2

Cystic or osteosclerotic lesions, or both, with a normal contour of the distal part of the femur or the proximal part of the tibia, or both, and with no subchondral flattening of the articular surface.

3

Presence of crescent sign. Flattening of the condyle or collapse of the subchondral bone plate with formation of a calcified plate and a clear sclerotic halo. Slightly narrowed joint space.

4

Osteoarthritic changes, such as spur formation and osteosclerosis, with a shallow concave articular surface at the osteonecrotic region