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Table 2 Associations between osteoporosis and comorbidities with adjusted odds ratios and 95% confidence intervals (GEDA 2012)

From: Prevalence and comorbidity of osteoporosis– a cross-sectional analysis on 10,660 adults aged 50 years and older in Germany

Comorbidity

Study population n (%a) (N = 10,660)

Osteoporosis population n (%a) (N = 911)

ORb (95% CI)

Arthrosis

3541 (34.5)

573 (63.2)

3.3 (2.6-4.1)***

Hypertension

4602 (44.2)

464 (51.3)

1.2 (1.0-1.5)

Chronic low back pain

2656 (26.8)

442 (49.6)

2.8 (2.3-3.5)***

Hypercholesterolemia

3092 (30.1)

334 (38.6)

1.5 (1.2-1.8)**

Coronary heart disease

1278 (13.7)

175 (21.0)

1.5 (1.1-2.0)**

Arthritis

799 (8.3)

171 (20.6)

3.0 (2.2-4.2)***

Any type of cancer

1334 (12.2)

154 (16.0)

1.2 (0.9-1.6)

Depression

911 (8.8)

128 (15.3)

2.3 (1.7-3.1)***

Chronic heart failure

600 (6.1)

110 (14.0)

2.3 (1.6-3.1)***

Diabetes mellitus

1418 (13.7)

122 (13.8)

0.9 (0.7-1.2)

Bronchial asthma

695 (7.1)

106 (12.2)

1.6 (1.2-2.2)**

Chronic bronchitis

701 (7.2)

119 (11.9)

1.6 (1.2-2.2)**

Stroke

437 (4.6)

67 (9.1)

1.8 (1.1-2.8)*

Myocardial infarction

596 (6.2)

59 (7.3)

1.0 (0.7-1.5)

Chronic liver disease

232 (2.1)

36 (3.8)

1.8 (1.0-3.2)*

  1. aWeighted results to represent the adult population in Germany
  2. bOdds ratio estimated from logistic regression adjusted for age, sex, education, BMI, smoking status and alcohol consumption, *** p < 0.001 ** p < 0.01 * p < 0.05. A separate regression model was fitted for each comorbidity