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Table 1 Summary of oncologic outcome in published series of ALT of extremities and trunk wall.

From: The role of surgical margins in atypical Lipomatous Tumours of the extremities

   

Local Recurrence

Dedifferentiation of recurrences

Metastatic disease

Mean time to recurrence (years)

Author

Year

Patients (n)

Wide Resection

Marginal Resection

Total

   

Azumi et al. [20]

1987

24

  

7/24 29%

0/7 0%

0

 

Weiss et al. [6]

1992

46

  

20/46 43%

3/20 15%

0

 

Lucas et al. [25]

1993

32

1/9 11%

14/23 61%

15/32 47%

1/15 7%

0

7

Rozental et al. [28]

2002

31

1/9 11%

15/22 68%

16/31 52%

4/16 25%

0

4,7

Kooby et al. [24]

2003

91

0/28 0%

5/63 8%

5/91 5%

3/5 60%

0

6,8

Bassett et al. [23]

2004

51

0/0

14/51 27%

14/51 27%

1/14 7%

0

4

Sommerville et al. [22]

2005

61

0/0

5/61 8%

5/61 8%

0/5 0%

0

3,2

Evans et al. [21]

2007

11

  

1/11 9%

0/1 0%

0

 

Zagars et al. [31]

2007

15

  

8/15 53%

0/8 0%

0

 

Billing et al. [5]

2008

51

 

4/51 8%

4/51 8%

0/4 0%

0

6,8

Mavrogenis et al. [17]

2011

47

0/8 0%

5/39 13%

5/47 11%

1/5 25%

0

6,1

Yamamoto et al. [8]

2012

40

0/34 0%

0/6 0%

0/40 0%

0/0 0%

0

 

Fisher et al. [32]

2013

63

59

4

14/63 22%

0/14 0%

0

 

Mussi et al. [33]

2014

171

5/95 5%

11/76 14%

16/171 9%

0/16 0%

0

 

Cassier et al. [26]

2014

283a

158

121

26/283 9%

0/26 0%

0

 

Kito et al. [29]

2015

41

7/11 64%

0/30 0%

7/41 17%

1/7 14%

0

7,9

Chang et al. [7]

2016

45

1/11 9%

7/34 21%

8/45 18%

0/8 0%

0

5,3

Current study

 

40

0/8 0%

3/32 9%

3/40 8%

0/3 0%

0

3,1

Total

 

1143

15/213 7% 430

83/488 17% 613

174/1143 15%

14/174 8%

0

5,5

  1. aIncluding patients with unknown margin status