From: Early detection of osteoarthritis in rabbits using MRI with a double-contrast agent
 | Before injection | After injection |  |
---|---|---|---|
 | SIR (SI of cartilage (× 104) / SI of fluid (× 104)) | SIR (SI of cartilage (× 104) / SI of fluid (× 104)) | P-value |
(a) | |||
 Control | 0.683 ± 0.092 (0.921 ± 0.171 / 1.360 ± 0.268) | 1.660 ± 0.169 (1.102 ± 0.188 / 0.680 ± 0.193) | 0.028 |
 2-w OA | 0.797 ± 0.061 (1.125 ± 0.200 / 1.416 ± 0.247) | 2.106 ± 0.344 (1.176 ± 0.306 / 0.573 ± 0.179) | 0.028 |
 4-w OA | 0.863 ± 0.150 (1.167 ± 0.088 / 1.377 ± 0.179) | 2.258 ± 0.322 (1.437 ± 0.324 / 0.641 ± 0.150) | 0.028 |
(b) | |||
 Control | 0.674 ± 0.186 (1.016 ± 0.219 / 1.546 ± 0.270) | 1.396 ± 0.187 (1.200 ± 0.251 / 0.865 ± 0.167) | 0.028 |
 2-w OA | 0.723 ± 0.104 (1.059 ± 0.234 / 1.464 ± 0.261) | 1.700 ± 0.374 (1.236 ± 0.376 / 0.729 ± 0.158) | 0.028 |
 4-w OA | 0.835 ± 0.104 (1.196 ± 0.216 / 1.438 ± 0.229) | 2.605 ± 0.212 (1.363 ± 0.350 / 0.525 ± 0.141) | 0.028 |