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Table 3 Hypothetical examples of combined data within scenarios

From: The influence of preoperative determinants on quality of life, functioning and pain after total knee and hip replacement: a pooled analysis of Dutch cohorts

Arthroplasty

Assessed outcome

Effect of age

Effect of BMI

Effect of preoperative status

Total effect on postoperative outcome (points)a

Scenario 1: A patient loses weight (X points) and increases preoperative status by Y points, this takes Z years

 X, Y, Z = 5 (e.g. in 5 years BMI decreases from 30 to 25, KOOS HRQoL/ functioning/ pain increases from 35 to 40)

  TKA

HRQoL

0

0

5*0.51

2.6

Functioning

0

0

5*0.31

1.6

Pain

0

5*0.47

5*0.18

3.3

  THA

HRQoL

5*−0.08

5*0.23

5*0.37

2.6

Functioning

5*−0.33

5*0.35

5*0.22

1.2

Pain

5*−0.18

5*0.36

5*0.15

1.7

 X, Y, Z = 10 (e.g. in 10 years BMI decreases from 35 to 25, KOOS HRQoL/ functioning/ pain increases from 35 to 45)

  TKA

HRQoL

0

0

10*0.51

5.1

Functioning

0

0

10*0.31

3.1

Pain

0

10*0.47

10*0.18

6.5

  THA

HRQoL

10*−0.08

10*0.23

10*0.37

5.2

Functioning

10*−0.33

10*0.35

10*0.22

2.4

Pain

10*−0.18

10*0.36

10*0.15

3.3

Scenario 2: A patient gains weight (X points) and decreases preoperative status by Y points, this takes Z years

 X, Y, Z = 5 (e.g. in 5 years BMI increases from 25 to 30, HOOS HRQoL/ functioning/ pain decreases from 40 to 35)

  TKA

HRQoL

0

0

5*−0.51

−2.6

Functioning

0

0

5*−0.31

−1.6

Pain

0

5*−0.47

5*−0.18

−3.3

  THA

HRQoL

5*−0.08

5*−0.23

5*−0.37

−3.4

Functioning

5*−0.33

5*−0.35

5*−0.22

−4.5

Pain

5*−0.18

5*−0.36

5*−0.15

−3.5

 X, Y, Z = 10 (e.g. in 10 years BMI increases from 25 to 35, HOOS HRQoL/ functioning/ pain decreases from 45 to 35)

  TKA

HRQoL

0

0

10*−0.51

−5.1

Functioning

0

0

10*−0.31

−3.1

Pain

0

10*−0.47

10*−0.18

−6.5

  THA

HRQoL

10*−0.08

10*−0.23

10*−0.37

−6.8

Functioning

10*−0.33

10*−0.35

10*−0.22

−9.0

Pain

10*−0.18

10*−0.36

10*−0.15

−6.9

  1. aOn a 0–100 scale