|
Author
|
Genotypes or alleles
|
n
|
Grade II
|
Grade III
|
Grade IV
|
χ2 or Z value a
|
P value
|
|---|
|
Zhang [10]
|
CC
|
192
|
94 (48.96%)
|
42 (21.88%)
|
56 (29.17%)
| | |
|
CT
|
79
|
48 (60.76%)
|
22 (27.85%)
|
9 (11.39%)
| | |
|
TT
|
41
|
20 (48.78%)
|
15 (36.59%)
|
6 (14.63%)
|
175.400
|
<0.001
|
|
C
|
463
|
236 (50.97%)
|
106 (22.89%)
|
121 (26.13%)
| | |
|
T
|
161
|
88 (54.66%)
|
52 (32.30%)
|
21 (13.04%)
|
−19.612
|
<0.001
|
|
Du [8]
|
CC
|
46
|
14 (30.43%)
|
12 (26.09%)
|
20 (43.48%)
| | |
|
CT
|
71
|
22 (30.99%)
|
18 (25.35%)
|
31 (43.66%)
| | |
|
TT
|
36
|
20 (55.56%)
|
9 (25.00%)
|
7 (19.44%)
|
66.501
|
<0.001
|
|
C
|
163
|
50 (30.67%)
|
42 (25.77%)
|
71 (43.56%)
| | |
|
T
|
143
|
62 (43.36%)
|
36 (25.17%)
|
45 (31.47%)
|
−5.346
|
<0.001
|
|
Xu [9]
|
CC
|
37
|
11 (29.73%)
|
12 (32.43%)
|
14 (37.84%)
| | |
|
CT
|
46
|
13 (28.26%)
|
15 (32.61%)
|
18 (39.13%)
| | |
|
TT
|
17
|
8 47.06%)
|
7 (41.18%)
|
2 (11.76%)
|
69.084
|
<0.001
|
|
C
|
101
|
30 (29.70%)
|
34 (33.66%)
|
37 (36.63%)
| | |
|
T
|
99
|
35 (35.35%)
|
33 (33.33%)
|
31 (31.31%)
|
−2.081
|
0.037
|
|
Meta-analyses b
|
CC
|
275
|
108 (39.27%)
|
68 (24.73%)
|
99 (36.00%)
| | |
|
CT
|
196
|
79 (40.31%)
|
55 (28.06%)
|
62 3(31.63%)
| | |
|
TT
|
94
|
48 (51.06%)
|
31 (32.98%)
|
15 (15.96%)
|
395.200
|
<0.001
|
|
C
|
730
|
273 (37.40%)
|
199 (27.26%)
|
258 (35.34%)
| | |
|
T
|
400
|
180 (45.00)
|
120 (30.00%)
|
100 (25.00%)
|
−28.366
|
<0.001
|
-
TRAIL tumor necrosis factor related apoptosis-inducing ligand, IDD intervertebral disc degeneration
-
a χ2 value was calculated by Kruskal-Wallis H, and Z value by Mann-Whitney Test
-
b Double-arcsine-transformed prevalence method was used to perform meta-analyses of prevalences
