Table 2 Rheumatoid Arthritis (RA) Participant Clinical Characteristics
Domain | Parameter | RA Baseline (n = 30) | RA 12-Months (n = 26) |
|---|---|---|---|
RA Diseases Duration | Months Since Diagnosis by a Rheumatologist [mean (SD), min-max] | 7.7 (4.9), 1–15* | Baseline Only |
Rheumatoid Arthritis Blood Markers | Anti-cyclic citrullinated protein antibodies (anti-CCP) and/or Rheumatoid Factor (RF) Positive [# (%)] | 22 (73%) | Baseline Only |
RA Medication Combinations | **8 DMARD Only [# (%)] | 13 (43%) | 22 (85%) |
DMARD + Glucocorticoid [# (%)] | 15 (50%) | 2 (7%) | |
DMARD + Biologic [# (%)] | 1 (3%) | 0 (0%) | |
DMARD + Glucocorticoid + Biologic [# (%)] | 0 (0%) | 0 (0%) | |
Single DMARD [# (%)] | 14 (47%) | 19 (73%) | |
Double DMARD [# (%)] | 7 (23%) | 4 (15%) | |
Triple DMARD [# (%)] | 8 (27%) | 1 (4%) | |
*** Glucocorticoids Only [# (%)] | 1 (3%) | 0 (0%) | |
**** Biologic Only [# (%)] | 0 (0%) | 1 (4%) | |
***** No RA medications [# (%)] | 0 (0%) | 1 (4%) | |
RA Medication Timing | Months to any DMARD once Diagnosed (n = 29) [mean (SD), min-max] | 0.1 (1), −4 to 3 | Baseline Only |
Months to Glucocorticoids Once Diagnosed (n = 16) [mean (SD), min-max] | −1.8 (3), −11 to 1 | Baseline Only | |
Months to Biologic Once Diagnosed (n = 1) | 8 | Baseline Only | |
Physical Evaluation – 28-Joint Active (Tender AND Swollen) Joint Count | Number participants with NO Tender AND Swollen Joints [n (%)] | 9 (30.0) | 15 (57.7) |
Number participants with at least one Tender AND Swollen Joint [n (%)] | 21 (70.0) | 11 (42.3) | |
Number of Tender AND Swollen Joints [mean (SD), min-max] | 4.2 (2.3), 1–9 | 3.6 (3.0), 1–9 | |
Stanford Health Assessment Questionnaire - Modified (MHAQ) [33] | Disability Index - 0 to 3 [mean (SD), min-max] | 0.59 (0.60), 0 to 2.13 | 0.48 (0.66), 0 to 2.00 |
Pain Visual Analog Scale (VAS) - 0 to 100 [mean (SD), min-max] | 21.2 (16.4), 0 to 65 | 20.4 (23.3), 0 to 89 | |
Global Functioning VAS - 0 to 100 [mean (SD), min-max] | 23.7 (18.8), 1 to 68 | 18.2 (21.7), 1 to 88 |