Fig. 5

Expressions of Bax, Bcl2, Casp3, Il1a, Il1b, Il6, Ccl2, Ccr2 and Tnfα and CD45+ cells during muscle regeneration in control and shockwave treated mice. a Bax, Bcl2 and Casp3 were highly expressed in the early phase of regeneration, and significantly different in the Li-SWT group on day 2, while the apoptotic potential, Bax/Bcl2 seemed lower in the Li-SWT group on day 3. Similarly Il1a and Tnfα were significantly higher expressed in the early phase of regeneration. The expression of Il1b, Il6, Ccl2 and Ccr2 showed similar expression pattern with highest levels from day 2–5 with no difference between the control and Li-SWT group. b Quantifications of CD45+ cells showed increased lymphocyte infiltration on day 2 and 3, with the only significant change in the number of CD45+ cells on day 21 in the SWT group. c Immunohistochemical stainings for CD45 on day 3. n = 3 in gene expressions and n = 4 in quantifications, * p < 0.05