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Table 2 Cox proportional hazard ratios

From: Risk factors for joint replacement in knee osteoarthritis; a 15-year follow-up study

 

Unadjusted

Adjusteda

Variable

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

JSN grade

2.2 (1.7 – 2.9)

<0.001

2.2 (1.7 – 3.0)

<0.001

Total radiological score

1.3 (1.1 – 1.4)

<0.001

1.3 (1.1 – 1.4)

<0.001

BML grade, b

1.5 (1.2 – 1.7)

<0.001

1.5 (1.2 – 1.8)

<0.001

Synovitis grade, c

1.5 (1.2 – 1.9)

0.001

1.5 (1.2 – 1.9)

0.001

Effusion grade, d

1.3 (1.1 – 1.5)

0.002

1.3 (1.1 – 1.5)

0.001

  1. CI confidence interval, JSN joint space narrowing, BML bone marrow lesion
  2. aAdjusted for sex, age and BMI (body mass index); b Ordered into a ten point ordinal scale (Grade 1 = 0 - 10% BML, grade 2 = >10 - 20% BML etc.); c Ordered into a five point ordinal scale (Grade 1 = 0 - <5; grade 2 = 5 - <10 etc.); d Ordered into an eight point ordinal scale (Grade 1 = 0 - <5; grade 2 = 5 - <10 etc.) (maximum effusion score = 38)