Fig. 3From: Structural effects of intra-articular TGF-β1 in moderate to advanced knee osteoarthritis: MRI-based assessment in a randomized controlled trialCoronal intermediate-weighted fat-suppressed MRI in treated patient at baseline (a) and 3 months (b) follow up show no improvement of cartilage damage in the medial tibiofemoral compartment (WORMS grade 6 at central medial femur; WORMS grade 5 at central medial tibia). There is a medial meniscal maceration/extrusion (arrow). There is a slight improvement of the subchondral bone marrow lesion/cysts at the central medial tibia (small arrows) and slight worsening of the subchondral bone marrow lesion/cysts at the central medial femur (long arrows). Note large medial osteophytesBack to article page