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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Structural effects of intra-articular TGF-β1 in moderate to advanced knee osteoarthritis: MRI-based assessment in a randomized controlled trial

Fig. 3

Coronal intermediate-weighted fat-suppressed MRI in treated patient at baseline (a) and 3 months (b) follow up show no improvement of cartilage damage in the medial tibiofemoral compartment (WORMS grade 6 at central medial femur; WORMS grade 5 at central medial tibia). There is a medial meniscal maceration/extrusion (arrow). There is a slight improvement of the subchondral bone marrow lesion/cysts at the central medial tibia (small arrows) and slight worsening of the subchondral bone marrow lesion/cysts at the central medial femur (long arrows). Note large medial osteophytes

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