Fig. 5
From: Establishment of rat ankle post-traumatic osteoarthritis model induced by malleolus fracture
OA biomarkers were detected by immunohistochemistry. a Type II collagen staining was lower in the fracture/dislocation group and in the fracture alone group than in the control group. b Strong type X collagen staining was detected in both experimental groups. c Strong MMP-13 staining was detected in both experimental groups. d Negative control. e Cell counting results indicated that the number of type X collagen and MMP-13 positive cells was increased in experimental groups than control groups. Values are the mean ± SD, * = P < 0.05 versus controls