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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: L161982 alleviates collagen-induced arthritis in mice by increasing Treg cells and down-regulating Interleukin-17 and monocyte-chemoattractant protein-1 levels

Fig. 2

Histological examination of mice hind paws. Blank CIA mice and PBS treated CIA mice showed hyperplasia of the synovial tissue, increased new blood vessels. Increased inflammatory cells infiltration, and cracked and denudated cartilage. Celecoxib and L161982 treated CIA mice showed less hyperplasia and inflammatory cells infiltration. Synovial hyperplasia in the articular cavity is marked in black arrows. Small maps (Magnification 50 μm) within each larger picture (Magnification 200 μm) highlight areas indicated by arrows. Slides were hematoxylin and eosin stained and magnified at 200 μm/50 μm)

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