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Table 1 DCE-MRI parameters of L5 vertebral bodies at five time points

From: Comparison of semi-quantitative and quantitative dynamic contrast-enhanced MRI evaluations of vertebral marrow perfusion in a rat osteoporosis model

Time point Control group OVX group t value P value
Emax
 Baseline 1.51 ± 0.19 1.51 ± 0.06 0.000 1.000
 Week 3 1.53 ± 0.34 1.35 ± 0.14 1.053 0.323
 Week 6 1.69 ± 0.19 1.30 ± 0.09 4.182 0.003#
 Week 9 1.58 ± 0.09 1.26 ± 0.16 3.971 0.004#
 Week 12 1.39 ± 0.16 1.35 ± 0.16 0.313 0.762
Ktrans (min−1)
 Baseline 0.29 ± 0.06 0.34 ± 0.03 −1.653 0.137
 Week 3 0.28 ± 0.08 0.18 ± 0.03* 2.646 0.029#
 Week 6 0.29 ± 0.07 0.20 ± 0.02* 2.691 0.027#
 Week 9 0.26 ± 0.08 0.18 ± 0.01* 2.462 0.039#
 Week 12 0.25 ± 0.06 0.16 ± 0.02* 2.724 0.041#
Ve (mL/100 mL)
 Baseline 0.36 ± 0.08 0.38 ± 0.09 −0.376 0.716
 Week 3 0.41 ± 0.18 0.25 ± 0.07 1.825 0.105
 Week 6 0.37 ± 0.08 0.29 ± 0.05 1.825 0.105
 Week 9 0.33 ± 0.08 0.22 ± 0.05* 2.600 0.032#
 Week 12 0.27 ± 0.05 0.25 ± 0.06 0.556 0.594
Kep (min−1)
 Baseline 0.79 ± 0.08 0.94 ± 0.18 −1.667 0.134
 Week 3 0.70 ± 0.29 0.84 ± 0.22 −0.868 0.410
 Week 6 0.77 ± 0.15 0.71 ± 0.18 0.560 0.591
 Week 9 0.80 ± 0.23 0.82 ± 0.24 −0.194 0.851
 Week 12 0.86 ± 0.16 0.65 ± 0.15 2.224 0.057
  1. Data are expressed as the means ± standard deviations. OVX group represents the rats underwent bilateral ovariectomy. Control group represents the rats underwent sham operation
  2. * P < 0 .05, versus baseline in the same group
  3. # P < 0.05, control group versus OVX group at the same time point