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Fig. 11 | BMC Musculoskeletal Disorders

Fig. 11

From: Bilateral muscle fiber and nerve influences by TNF-alpha in response to unilateral muscle overuse – studies on TNF receptor expressions

Fig. 11

a, b The figures represent double staining (IHC) of a vessel, with antibodies towards TNFR1 and CD31. The section in (b) is also labelled with DAPI. TNFR1 is expressed in cell nuclei of the smooth muscle (arrows) but not in the endothelium of the vessel. Sample from experimental animal; experimental side (6 week group). Orig. magnif. ×500. c, d. Staining with antibody against TNFR2 (green colour) (c). d represents double staining; staining with antibodies against TNFR2 (green colour) and CD31 (red colour). TNFR2 is seen in the outer (smooth muscle) part of blood vessel walls in both (c) and (d) but not in the inner (intima) parts. There is expression of CD31 in the inner layer (d). Specimens from 6 week experimental group, contralateral side. Orig. magnif. ×300 (c), ×500 (d)

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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