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Table 2 Comparison between the continuous infusion group and bolus injection group

From: Comparison of continuous infusion versus bolus injection of factor concentrates for blood management after total knee arthroplasty in patients with hemophilia

 

Continuous infusion

(n = 21)

Bolus injection

(n = 21)

p

Total amount of coagulation factor concentrates (IU/kg)

Mean ± SD

 Operation day 0–3

460.23 ± 72.721

359.19 ± 86.686

0.000*

 Operation day 0–5

604.03 ± 112.836

467.85 ± 101.157

0.000*

Hemoglobin (g/dL)

Mean ± SD

 Pre-operation

14.71 ± 0.864

15.05 ± 1.963

0.468

 Operation day (post)

13.66 ± 1.188

12.79 ± 1.891

0.081

 Hemoglobin drop

1.14 ± 0.961

2.26 ± 1.238

0.002*

 Drained blood volume at postoperation day 1 (mL)

574.76 ± 286.855

788.33 ± 351.494

0.037*

Mean ± SD

 Packed RBC transfusion

  No. (n)

1 / 21

5 / 21

0.184

  Volume (mL/kg)

0.81 ± 3.740

3.56 ± 7.015

0.120

  1. SD Standard deviation, RBC Red blood cell
  2. *p < 0.05