Effect of vitamin E on oxidative stress level in blood, synovial fluid, and synovial tissue in severe knee osteoarthritis: a randomized controlled study

Table 5 Oxidative stress and antioxidative capacity measurements from synovial fluid

	Group A (placebo)	Group B (vitamin E)	P value
Oxidative agents and products
- Nitrite (μM) - Malondialdehyde (μM)	5.94 ± 1.09 1.42 ± 0.12	5.24 ± 0.91 1.06 ± 1.08	0.63 0.01^a
Antioxidative agents
- Alpha-tocopherol (μg/ml) - FRAP (mM) - TEAC (mM)	4.51 ± 0.31 999.10 ± 39.51 1.89 ± 0.06	7.03 ± 0.86 1103 ± 44.77 2.19 ± 0.1	<0.01^a 0.09 0.01^a

Data are presented as mean ± standard deviation
P value represent the test between groups
FRAP ferric reducing antioxidant power, TEAC Trolox equivalent antioxidant capacity
^aStatistically significant

ISSN: 1471-2474