From: The efficacy and safety of tranexamic acid in revision total knee arthroplasty: a meta-analysis
Outcome | Studies | Groups (TXA/Placebo) | Overall effect | Heterogeneity | |||
---|---|---|---|---|---|---|---|
Effect estimate | 95% CI | p-Value | I2(%) | p-Value | |||
Transfusion requirements | 4 | 352/317 | −0.25 | −0.43, −0.08 | 0.005 | 85 | 0.0002 |
Drainage volume | 2 | 63/72 | −321.07 | −445.13, −197.01 | 0.005 | 0 | 0.68 |
Hb reduction | 2 | 290/221 | −0.52 | −0.79, −0.25 | 0.0001 | 62 | 0.11 |
Length of hospital stay | 3 | 309/249 | −2.36 | −4.00, −0.71 | 0.005 | 70 | 0.04 |
Deep venous thrombosis | 3 | 308/274 | 0.00 | −0.01, 0.02 | 0.69 | 0 | 0.97 |
Pulmonary embolism | 2 | 289/246 | −0.01 | −0.03, 0.01 | 0.18 | 0 | 0.89 |