Table 1 Clinical characteristics, treatment strategies and outcomes of the five cases of prosthetic joint infection caused by Granulicatella adiacens
From: Prosthetic joint infection caused by Granulicatella adiacens: a case series and review of literature
Number of cases | Age (years) | Sex | Location of Infection | Time delay between arthroplasty implantation and infection onset | Dental care before infection onset | Microbiologic diagnostics of G. adiacens | Associated microorganisms | Surgery treatment options | Antibiotics | Outcomes |
|---|---|---|---|---|---|---|---|---|---|---|
Our 1st case | 75 | Male | Hip arthroplasty | 4 years | Yes | Microbial culture of surgical biopsies was negative. | Parvimonas micra | Two-stage prosthesis exchange | Amoxicillin and clindamycin | Cured |
16S rRNA gene sequencing on synovial fluid was positive. | ||||||||||
Our 2nd case | 65 | Male | Knee arthroplasty | 2 years | No | Maldi-Tof mass spectrometry on bacterial colonies. | Staphylococcus capitis | One-stage prosthesis exchange | Rifampicin and clindamycin | Cured |
Our 3rd case | 44 | Female | Hip arthroplasty | 10 years | No | Maldi-Tof mass spectrometry on bacterial colonies | Klebsiella pneumoniae | Debridement, antibiotics, irrigation, and retention of the prosthesis (DAIR) | Imipenem-cisplatin then ciprofloxacin and amoxicillin | Cured |
16S rRNA gene sequencing on synovial fluid was positive. | ||||||||||
Riede et al., 2004 [12] | 43 | Male | Knee arthroplasty | 3 years | No | Microbial culture of surgical biopsies was positive but the microorganism could not be identified reliably by phenotypic methods | No | Two-stage prosthesis exchange | Amoxicillin, amikacin and rifampicin | Cured |
16S rRNA gene sequencing on bacterial colonies | ||||||||||
Mougari et al., 2013 [13] | 55 | Male | Knee arthroplasty | 10 years | Yes | Microbial culture of surgical biopsies was negative. | No | Two-stage prosthesis exchange | Amoxicillin and rifampicin | Cured |
16S rRNA gene sequencing on synovial fluid was positive. |