Fig. 5From: Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosisRelationships of mean sCTX inhibition over 24 h with observed increases in BMD over 1 year in the OCEAN study [16]. Relationships are shown for % Emax for sCTX inhibition with increases in (a) lumbar spine (LS1–4) BMD and (b) hip BMD. BMD data in the OCEAN study were reported by Eastell et al. [16]Back to article page