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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint

Fig. 2

Mitochondrial dysfunction increases CD68 (panel a) positive cells and IL-8 (panel b) in the synovial membrane. a Representative samples of CD68 immunohistochemistry in synovial membrane. b Synovium sections were analyzed by immunohistochemistry for IL-8. Quantitative analysis of CD68 (c) and IL-8 (d) positive cells. Values represent mean ± SEM (n = 5 independent synovial tissues). To assess non-immune non-specific binding negative control was included in each experiment. * P ≤ 0.05 vs contralateral vehicle-injected knees. LPS, lipopolysaccharide; OLI, oligomycin

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