Variable | Description | Cure of infectiona | p-valueb | |||||
---|---|---|---|---|---|---|---|---|
Yes | No | |||||||
n | mean or % | SD | n | mean or % | SD | |||
Gender | Male | 56 | 72.7 | 21 | 72.4 | 0.9743 | ||
Female | 21 | 27.3 | 8 | 27.6 | ||||
Age | 77 | 53.2 | 18.9 | 29 | 55.8 | 17.9 | 0.5588 | |
Stay at ICU | days | 77 | 3.0 | 5.2 | 29 | 5.6 | 7.3 | 0.0790 |
Initial procedure | Open | 1 | 1.3 | 2 | 6.9 | 0.1810 | ||
Closed | 76 | 98.7 | 27 | 93.1 | ||||
Tissue damage | Open Grade 0-2 | 11 | 14.3 | 8 | 27.6 | 0.0437 | ||
Open Grade 3-4 | 7 | 9.1 | 6 | 20.7 | ||||
Closed | 59 | 76.6 | 15 | 51.8 | ||||
Identification of a | Yes | 66 | 85.7 | 26 | 89.7 | 0.7535 | ||
microbial strain | No | 11 | 14.3 | 3 | 10.3 | |||
Presence of a bacterial mixture | Yes | 12 | 15.6 | 9 | 31.0 | 0.2016 | ||
No | 54 | 70.1 | 17 | 58.6 | ||||
No detectable germ | 11 | 14.3 | 3 | 10.3 | ||||
Change in microbial strain | Yes | 65 | 84.4 | 17 | 58.6 | 0.0047 | ||
No | 12 | 15.6 | 12 | 41.4 | ||||
Gram stain | Positive | 57 | 74.0 | 17 | 58.6 | 0.0746 | ||
Negative | 9 | 11.7 | 9 | 31.0 | ||||
No detectable germ | 11 | 14.3 | 3 | 10.4 | ||||
Bacterial metabolism | Aerobic | 3 | 3.8 | 4 | 13.8 | 0.0309 | ||
Anaerobic | 1 | 1.3 | 2 | 6.9 | ||||
Facultative anaerobic | 60 | 77.9 | 16 | 55.2 | ||||
Facultative aerobic | 2 | 2.6 | 3 | 10.3 | ||||
No detectable germ | 11 | 14.3 | 4 | 13.8 | ||||
Bacterial load | Plentiful | 18 | 23.4 | 9 | 31.0 | 0.9095 | ||
Numerous | 25 | 32.5 | 7 | 24.1 | ||||
Sporadic | 20 | 26.0 | 8 | 27.6 | ||||
Enrichment | 3 | 3.9 | 1 | 3.4 | ||||
No detectable germ | 11 | 14.3 | 4 | 13.8 | ||||
Number of lavages until eradication | sponge changes 0 | 33 | 42.9 | 18 | 62.1 | 0.0431 | ||
sponge changes 1 | 20 | 26.0 | 6 | 20.7 | ||||
sponge changes 2 | 14 | 18.2 | 0 | 0.0 | ||||
sponge changes ≥3 times | 8 | 10.4 | 3 | 10.3 | ||||
Never be eradicated | 2 | 2.6 | 2 | 6.9 | ||||
CRP Initial | [mg/l] | 72 | 78.2 | 92.1 | 25 | 69.6 | 78.4 | 0.8112 |
CRP Maximum | [mg/l] | 76 | 128.8 | 101.7 | 25 | 137.5 | 94.6 | 0.4547 |
CRP Discharge | [mg/l] | 75 | 16.3 | 23.6 | 26 | 46.1 | 52.1 | 0.0077 |
CRP Discharge | ≤20 mg/l | 58 | 77.3 | 12 | 46.2 | 0.0036 | ||
>20 mg/l | 17 | 22.7 | 14 | 53.8 | ||||
Time point of infection | Early | 49 | 63.3 | 16 | 57.1 | 0.5446 | ||
Late | 28 | 36.7 | 12 | 42.9 | ||||
Extent of infection | Superficial | 2 | 2.6 | 1 | 3.4 | 1.000 | ||
Deep | 75 | 97.4 | 28 | 96.6 | ||||
Metabolic diseasec | Yes | 12 | 15.6 | 7 | 24.1 | 0.3061 | ||
No | 65 | 84.4 | 22 | 75.9 | ||||
Re-infection | Yes | 23 | 29.9 | 14 | 48.3 | 0.0764 | ||
No | 54 | 70.1 | 15 | 51.7 | ||||
Implantat preservation | After fracture consolidation | 40 | 53.3 | 7 | 24.1 | 0.0073 | ||
Before fracture consolidation | 35 | 46.6 | 22 | 75.9 |