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Table 2 Summary of the collected data displaying distribution of the parameters investigated in the group with a cured infection and the group without.

From: Factors influencing treatment success of negative pressure wound therapy in patients with postoperative infections after Osteosynthetic fracture fixation

Variable

Description

Cure of infectiona

p-valueb

Yes

No

n

mean or %

SD

n

mean or %

SD

Gender

Male

56

72.7

 

21

72.4

 

0.9743

Female

21

27.3

 

8

27.6

  

Age

 

77

53.2

18.9

29

55.8

17.9

0.5588

Stay at ICU

days

77

3.0

5.2

29

5.6

7.3

0.0790

Initial procedure

Open

1

1.3

 

2

6.9

 

0.1810

Closed

76

98.7

 

27

93.1

  

Tissue damage

Open Grade 0-2

11

14.3

 

8

27.6

 

0.0437

Open Grade 3-4

7

9.1

 

6

20.7

  

Closed

59

76.6

 

15

51.8

  

Identification of a

Yes

66

85.7

 

26

89.7

 

0.7535

microbial strain

No

11

14.3

 

3

10.3

  

Presence of a bacterial mixture

Yes

12

15.6

 

9

31.0

 

0.2016

No

54

70.1

 

17

58.6

  

No detectable germ

11

14.3

 

3

10.3

  

Change in microbial strain

Yes

65

84.4

 

17

58.6

 

0.0047

No

12

15.6

 

12

41.4

  

Gram stain

Positive

57

74.0

 

17

58.6

 

0.0746

Negative

9

11.7

 

9

31.0

  

No detectable germ

11

14.3

 

3

10.4

  

Bacterial metabolism

Aerobic

3

3.8

 

4

13.8

 

0.0309

Anaerobic

1

1.3

 

2

6.9

  

Facultative anaerobic

60

77.9

 

16

55.2

  

Facultative aerobic

2

2.6

 

3

10.3

  

No detectable germ

11

14.3

 

4

13.8

  

Bacterial load

Plentiful

18

23.4

 

9

31.0

 

0.9095

Numerous

25

32.5

 

7

24.1

  

Sporadic

20

26.0

 

8

27.6

  

Enrichment

3

3.9

 

1

3.4

  

No detectable germ

11

14.3

 

4

13.8

  

Number of lavages until eradication

sponge changes 0

33

42.9

 

18

62.1

 

0.0431

sponge changes 1

20

26.0

 

6

20.7

  

sponge changes 2

14

18.2

 

0

0.0

  

sponge changes ≥3 times

8

10.4

 

3

10.3

  

Never be eradicated

2

2.6

 

2

6.9

  

CRP Initial

[mg/l]

72

78.2

92.1

25

69.6

78.4

0.8112

CRP Maximum

[mg/l]

76

128.8

101.7

25

137.5

94.6

0.4547

CRP Discharge

[mg/l]

75

16.3

23.6

26

46.1

52.1

0.0077

CRP Discharge

≤20 mg/l

58

77.3

 

12

46.2

 

0.0036

>20 mg/l

17

22.7

 

14

53.8

  

Time point of infection

Early

49

63.3

 

16

57.1

 

0.5446

Late

28

36.7

 

12

42.9

  

Extent of infection

Superficial

2

2.6

 

1

3.4

 

1.000

 

Deep

75

97.4

 

28

96.6

  

Metabolic diseasec

Yes

12

15.6

 

7

24.1

 

0.3061

No

65

84.4

 

22

75.9

  

Re-infection

Yes

23

29.9

 

14

48.3

 

0.0764

No

54

70.1

 

15

51.7

  

Implantat preservation

After fracture consolidation

40

53.3

 

7

24.1

 

0.0073

Before fracture consolidation

35

46.6

 

22

75.9

  
  1. SD = standard deviation, an total = 106, b in all analysis two-tailed tests with a significance level of 0.05 were used, c metabolic diseases = kidney diseases, liver diseases and diabetes mellitus