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Table 2 Summary of the collected data displaying distribution of the parameters investigated in the group with a cured infection and the group without.

From: Factors influencing treatment success of negative pressure wound therapy in patients with postoperative infections after Osteosynthetic fracture fixation

Variable Description Cure of infectiona p-valueb
Yes No
n mean or % SD n mean or % SD
Gender Male 56 72.7   21 72.4   0.9743
Female 21 27.3   8 27.6   
Age   77 53.2 18.9 29 55.8 17.9 0.5588
Stay at ICU days 77 3.0 5.2 29 5.6 7.3 0.0790
Initial procedure Open 1 1.3   2 6.9   0.1810
Closed 76 98.7   27 93.1   
Tissue damage Open Grade 0-2 11 14.3   8 27.6   0.0437
Open Grade 3-4 7 9.1   6 20.7   
Closed 59 76.6   15 51.8   
Identification of a Yes 66 85.7   26 89.7   0.7535
microbial strain No 11 14.3   3 10.3   
Presence of a bacterial mixture Yes 12 15.6   9 31.0   0.2016
No 54 70.1   17 58.6   
No detectable germ 11 14.3   3 10.3   
Change in microbial strain Yes 65 84.4   17 58.6   0.0047
No 12 15.6   12 41.4   
Gram stain Positive 57 74.0   17 58.6   0.0746
Negative 9 11.7   9 31.0   
No detectable germ 11 14.3   3 10.4   
Bacterial metabolism Aerobic 3 3.8   4 13.8   0.0309
Anaerobic 1 1.3   2 6.9   
Facultative anaerobic 60 77.9   16 55.2   
Facultative aerobic 2 2.6   3 10.3   
No detectable germ 11 14.3   4 13.8   
Bacterial load Plentiful 18 23.4   9 31.0   0.9095
Numerous 25 32.5   7 24.1   
Sporadic 20 26.0   8 27.6   
Enrichment 3 3.9   1 3.4   
No detectable germ 11 14.3   4 13.8   
Number of lavages until eradication sponge changes 0 33 42.9   18 62.1   0.0431
sponge changes 1 20 26.0   6 20.7   
sponge changes 2 14 18.2   0 0.0   
sponge changes ≥3 times 8 10.4   3 10.3   
Never be eradicated 2 2.6   2 6.9   
CRP Initial [mg/l] 72 78.2 92.1 25 69.6 78.4 0.8112
CRP Maximum [mg/l] 76 128.8 101.7 25 137.5 94.6 0.4547
CRP Discharge [mg/l] 75 16.3 23.6 26 46.1 52.1 0.0077
CRP Discharge ≤20 mg/l 58 77.3   12 46.2   0.0036
>20 mg/l 17 22.7   14 53.8   
Time point of infection Early 49 63.3   16 57.1   0.5446
Late 28 36.7   12 42.9   
Extent of infection Superficial 2 2.6   1 3.4   1.000
  Deep 75 97.4   28 96.6   
Metabolic diseasec Yes 12 15.6   7 24.1   0.3061
No 65 84.4   22 75.9   
Re-infection Yes 23 29.9   14 48.3   0.0764
No 54 70.1   15 51.7   
Implantat preservation After fracture consolidation 40 53.3   7 24.1   0.0073
Before fracture consolidation 35 46.6   22 75.9   
  1. SD = standard deviation, an total = 106, b in all analysis two-tailed tests with a significance level of 0.05 were used, c metabolic diseases = kidney diseases, liver diseases and diabetes mellitus