Rheumatoid factors do not predict cardiovascular disease and mortality in the general population in the Busselton Health Survey

Table 2 Estimated adjusted hazard ratios for rheumatoid factor (RF) and rheumatoid arthritis (RA) in relation to CHD and CVD events in the cohort free of CHD and stroke at baseline in 1972. Table shows hazard ratio, 95% CI and p-value

	CHD		CVD
Risk factor	HR^a (95% CI)	p-value	HR^a (95% CI)	p-value
RA (not adjusted for RF)	1.01 (0.79, 1.28)	0.943	1.01 (0.83, 1.22)	0.950
RA (adjusted for RF)	1.01 (0.79, 1.28)	0.951	1.01 (0.83, 1.21)	0.953
RF score^b (not adjusted for RA)	1.02 (0.95, 1.10)	0.522	1.03 (0.97, 1.09)	0.352
RF score^b (adjusted for RA)	1.02 (0.95, 1.10)	0.523	1.03 (0.97, 1.09)	0.352
RF positive (not adjusted for RA)	1.05 (0.87, 1.28)	0.610	1.04 (0.89, 1.21)	0.633
RF positive (adjusted for RA)	1.05 (0.87, 1.28)	0.611	1.04 (0.89, 1.21)	0.633
RF positive (for RA = no)^c	1.07 (0.87, 1.31)	0.516	1.02 (0.87, 1.20)	0.787
RF positive (for RA = yes)^c	0.92 (0.51, 1.64)	0.770	1.15 (0.75, 1.77)	0.512

^aFrom Cox model adjusted for age, sex, smoking, BMI, SBP, hypertension medication, cholesterol and diabetes
^bHR is for an increase of one in the score
^cFrom Cox model that included interaction between RF and RA

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