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Table 6 Variation of serum Coll2-1 between D-10 and D180 in the FAS population without handling the missing values

From: Reduction of the Serum Levels of a Specific Biomarker of Cartilage Degradation (Coll2-1) by Hyaluronic Acid (KARTILAGE® CROSS) Compared to Placebo in Painful Knee Osteoarthritis Patients: the EPIKART Study, a Pilot Prospective Comparative Randomized Double Blind Trial

 

IAHA

N = 40 at D-10

N = 35 at D180

Saline solution

N = 41 at D-10

N = 36 at D180

P value

Test

Serum Coll2-1 at D-10

840.3 ± 375.8

(N = 40)

766.1 ± 359.2

(N = 41)

0.3663

ANOVA

Serum Coll2-1 at D180

784.0 ± 223.2

(N = 37)

865.1 ± 343.9

(N = 36)

0.244

ANOVA

Adjustment on basal value

−34.5 ± 49.7

43.5 ± 49.0

0.2689

0.0473*

ANCOVA

Wilcoxona

  1. aShapiro-Wilk normality test < 0.0001, basal value was used as covariate
  2. *p < 0.05