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Table 6 Variation of serum Coll2-1 between D-10 and D180 in the FAS population without handling the missing values

From: Reduction of the Serum Levels of a Specific Biomarker of Cartilage Degradation (Coll2-1) by Hyaluronic Acid (KARTILAGE® CROSS) Compared to Placebo in Painful Knee Osteoarthritis Patients: the EPIKART Study, a Pilot Prospective Comparative Randomized Double Blind Trial

  IAHA
N = 40 at D-10
N = 35 at D180
Saline solution
N = 41 at D-10
N = 36 at D180
P value Test
Serum Coll2-1 at D-10 840.3 ± 375.8
(N = 40)
766.1 ± 359.2
(N = 41)
0.3663 ANOVA
Serum Coll2-1 at D180 784.0 ± 223.2
(N = 37)
865.1 ± 343.9
(N = 36)
0.244 ANOVA
Adjustment on basal value −34.5 ± 49.7 43.5 ± 49.0 0.2689
0.0473*
ANCOVA
Wilcoxona
  1. aShapiro-Wilk normality test < 0.0001, basal value was used as covariate
  2. *p < 0.05